Effect of adjunctive low level laser therapy on gingival crevicular fluid levels of sclerostin, osteoprotegerin and receptor activator of nuclear factor- Îºb ligand in the non surgical management of periodontitis - a randomized controlled trial.

Dr KEERTHANA CHAND C S0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年5月2日

试验速览

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•Groups 1 and 2
•Systemically healthy male and female subjects in the age group of 20 to 60 years.
•Presence of a minimum of 20 teeth in the oral cavity.
•Generalised periodontitis in stage3 gradeB as described by the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions, and published by the American Academy of Periodontology (AAP).
•Systemically healthy male and female subjects in the age group of 20 to 60 years.
•Presence of a minimum of 20 teeth in the oral cavity.
•Periodontally healthy controls i.e clinically healthy gingiva with intact periodontium characterized as described by the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions and published by the American Academy of Periodontology (AAP).

•Patients with a history of systemic diseases including bone-related and collagen-metabolic disorders that compromise sclerostin, OPG, or RANKL levels.
•Patients on steroid therapy or any other medications affecting bone metabolism.
•Current and former smokers.
•Chronic consumers of alcohol.
•Pregnant or lactating women.
•Subjects with intake of systemic antibiotics and anti-inflammatory drugs 3 months prior to their recruitment into study.
•Subjects with a history of periodontal therapy in any form 6 months prior to their recruitment to the study.

发起方

Dr KEERTHANA CHAND C S