Study on effects of cytokine targeted therapy on periodontal condition in patients with rheumatoid arthritis
Not Applicable
- Conditions
- Rheumatoid arthritis, Periodontitis
- Registration Number
- JPRN-UMIN000013750
- Lead Sponsor
- Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
1.Individuals who had received scaling and root planing within the previous 3 months before the study starts. 2.Individuals who had taken systemic antibiotics or anti-inflammatory drugs within 3 months before the study starts. 3.Individuals with severe systemic diseases 4.Individuals who are or suspected to be pregnant. 5.Individuals who are considered not eligible for the present study due to any reasons by the investigators.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gingival index Bleeding on probing Probing pocket depth Clinical attachment level
- Secondary Outcome Measures
Name Time Method Serum markers hsCRP IL-6 TNF-alpha MMP-3