Perioperative Pain Alleviation of Forearm Fractures Using a Combination of Hematoma Block and Intravenous Regional Anesthesia by Ketamine and Lidocaine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- pain assessment
研究概览
简要总结
fractures of upper limb induce much pain . A lot of modalities are available to alleviate pain. fracture hematoma block, and intravenous regional anesthesia seem to be cost effective and attractive options
详细描述
Fractures of the forearm are extremely common, Pain relief is of utmost importance in forearm fractures which may need manipulation immediately for reduction followed by operative intervention
The characteristic features of ideal analgesia during reduction are determined by safety, simplicity, affectivity and costs. Giventhe logistic difficulty of providing such anesthesia to such large number of patients simpler alternatives to conventional anesthesia have been tried. Hematoma Block alone, Hematoma Block with sedation, Bier's Block (Intravenous regional anesthesia), regional nerve blocks, sedation have been compared to general anesthesia to evaluate the efficacy, effectiveness, safety in treating such patients
Amongst various techniques, HB and IVRA are attractive options. However, while HB has been demonstrated to be safe simple and has been used effectively for treatment of radius fractures in ER and for immediate pain relief it doesn't provide muscular relaxation and may not be sufficient for any operative intervention
IVRA is suitable for operations of the distal extremities, in situations where it is safe and easy to apply an occlusive tourniquet. The primary advantages of IVRA are its simplicity, reliability, and cost-effectiveness. . It is a regional anesthetic technique that is easy to perform, with success rates varying between 94% and 98%.For these reasons, it remains a popular choice among anesthesiologists.
A combination of blocks is usually done to overcome the deficiencies of individual blocks and to improve operating conditions or to prolong post operative analgesia. However the use of dual technique of IVRA and HB with local anesthetic only offered near absence of post operative analgesia
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients aged more than 18 years old.
- •American Society of Anesthesiologists (ASA) physical status I or II.
- •Patients scheduled for closed fracture of distal upper extremity within 7 days, requiring open or closed reduction and internal fixation.
- •Patients scheduled for procedure lasting less than 90 minutes.
排除标准
- •Patients having cardiovascular co-morbidities.
- •Compound or contaminated fracture.
- •Peripheral vascular disease, sickle cell disease or coagulation disorders.
- •Allergy to the local anesthetics or to the drugs used in the study.
研究组 & 干预措施
Ketamine in hematoma block
Ketamine used in hematoma block
干预措施: ketamine in hematoma block (Drug)
ketamine intravenous anesthesia
ketamine used in local intravenous anesthesia
干预措施: ketamine in local intravenous anesthesia (Drug)
lidocaine intravenous anesthesia
2.5 mg/kg of lidocaine 2% diluted with saline to a total volume of 40 ml.
干预措施: Lidocaine Hydrochloride (Drug)
结局指标
主要结局
pain assessment
时间窗: 24 hours
pain will be assessed by numerical rating scale
次要结局
- analgesia requirement(24 hours)
研究者
Mohammed mamdouh mohammed mahmoud
Dr
Assiut University
