Comparison of nalbuphine and buprenorphine as adjuvants to ropivacaine in interscalenebrachial plexus block
Phase 2
Not yet recruiting
- Conditions
- Health Condition 1: S420- Fracture of clavicleHealth Condition 2: S424- Fracture of lower end of humerusHealth Condition 3: S423- Fracture of shaft of humerusHealth Condition 4: S422- Fracture of upper end of humerus
- Registration Number
- CTRI/2021/03/031818
- Lead Sponsor
- Dr Anitha A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anaesthesiologists (ASA) physical status I and
II scheduled for upper limb surgery
Exclusion Criteria
Any neurological deficit, peripheral neuropathies, myopathies or
chronic pain in the operative limb.
History of anaphylaxis to local anaesthetics or known allergy to any
of the study drugs to be used.
Any history of bleeding diathesis or coagulation abnormalities.
Any skin infection or local disease at the needle insertion site. BMI more than 35kg/sq-m, failure to achieve adequate block within 30 mins of administration.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to onset of sensory and motor block. <br/ ><br>Duration of sensory and motor block. <br/ ><br>Duration of analgesiaTimepoint: Time to onset of sensory and motor block. <br/ ><br>Duration of sensory and motor block. <br/ ><br>Duration of analgesia
- Secondary Outcome Measures
Name Time Method Pain scores <br/ ><br>Adverse effects- Hypotension, Bradycardia, <br/ ><br>Tachycardia, Hypoxemia, Sedation, Nausea, <br/ ><br>Vomiting, Pruritis, Skin Rash, Dry mouth, <br/ ><br>DyspneaTimepoint: Pain assessed by Visual Analogue scale <br/ ><br>Hypotension(noninvasive blood pressure less <br/ ><br>than 20% of baseline) <br/ ><br>Bradycardia(heart rate less than 60beats/minute) <br/ ><br>Tachycardia(heart rate more than <br/ ><br>100beats/minute) <br/ ><br>Hypoxemia(oxygen saturation less than 90%) <br/ ><br>Sedation assessed by Modified Ramsay <br/ ><br>sedation scale <br/ ><br>Nausea and vomiting assessed by Nausea and <br/ ><br>vomiting scale