"Re-instrumentation vs Flap Surgery"
Not Applicable
Completed
- Conditions
- PeriodontitisPeriodontal Pocket
- Registration Number
- NCT05460988
- Lead Sponsor
- University of Florence
- Brief Summary
There are no studies comparing reinstrumentation and flap surgery for the treatment of residual periodontal pockets.
The aim of this RCT is to compare the re-instrumentation vs the flap surgery in terms of PD reduction, CAL gain, gingival recession, need of an additional surgery and pocket closure. Moreover, PROMs will be evaluated
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
- Age ≥18aa
- Patients with periodontal disease
- Less than 20 cigarettes/day
- No systemic antibiotic therapy in the last 3 months
- At least one interdental site showing PD≥5mm after the non surgical periodontal initial therapy. Infrabony component of the defect ≤3mm at x-ray
- Full-mouth plaque score and full-mouth bleeding score <15% at baseline (re-evaluation) measured at six sites per tooth
- No previous periodontal surgery at the experimental tooth
Exclusion Criteria
- Connective tissue diseases
- Diabetes
- Pregnancy or lactating
- Furcation involvement
- Crowned tooth
- Severe tooth mobility (class III)
- Radiographical horizontal bone resorption exceeding the 50% of the root
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method PD change 12 months after the procedure change in periodontal probing depth (in mm)
- Secondary Outcome Measures
Name Time Method CAL change 12 months after the procedure change in clinical attachment level (in mm)
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie PD reduction in re-instrumentation versus flap surgery for residual periodontal pockets?
How does re-instrumentation compare to flap surgery in terms of CAL gain and long-term pocket closure in periodontitis patients?
Are there specific biomarkers that predict better outcomes with flap surgery over re-instrumentation in chronic periodontitis?
What are the potential adverse events associated with flap surgery for residual periodontal pockets and how are they managed?
What combination therapies or adjunctive treatments are being explored alongside re-instrumentation or flap surgery for periodontal pocket management?
Trial Locations
- Locations (1)
University of Florence
🇮🇹Florence, Italy
University of Florence🇮🇹Florence, Italy