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The Accuracy of Ultrasonic Viscoelastic Imaging in Evaluating the Severity of Chronic Kidney Diseases

Completed
Conditions
Chronic Kidney Disease(CKD)
Registration Number
NCT06961162
Lead Sponsor
Peking University Third Hospital
Brief Summary

The goal of this observational study is to learn about the role of ultrasonic viscoelastic parameters in the assessing the severity of chronic kidney disease. The main question it aims to answer is:

The accuracy of ultrasonic viscoelastic parameters in evaluating the degree of renal fibrosis and inflammation.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
47
Inclusion Criteria
  • (1) fulfilled the diagnostic criteria for CKD (disease course > 3months); (2) underwent renal biopsy, (3) a prior 2D-SWE evaluation preceding the renal biopsy, and (4) obtained informed written consent.
Exclusion Criteria
  • (1) the presence of multiple renal cysts, calculi, hydronephrosis, or masses that could potentially interfere with the analysis conducted through 2D-SWE: (2) unsuccessful 2D-SWE measurements ;(3) biopsy specimens deemed inadequate due to insufficient length (less than 10 mm) or fewer than 10 glomeruli, and (4) incomplete clinical data.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
renal fibrosis degreeone week
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Ultrasound, Peking University Third Hospital

🇨🇳

Beijing, Beiing, China

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