Comparison Between Land-based and Water-based Exercises for Knee Osteoarthritis: Randomized Controlled Trial

Phase 1

Completed

• Conditions: Knee Osteoarthritis
• Interventions: Other: water-based exercises; Other: land-based exercises

• Registration Number: NCT02295605
• Lead Sponsor: University of Nove de Julho

Brief Summary

Forty six patients with knee osteoarthritis will be randomly allocated into two groups: water-based exercises and land-based exercises. Both of them will receive a strengthening exercise protocol for lower limb muscles. A blind investigator will assess the patients before and immediately after, 3 months and 6 months following the interventions. The main outcomes will be pain, function and strength.

Detailed Description

Forty six patients with knee osteoarthritis will be randomly allocated into two groups: water-based exercises and land-based exercises. Both of them will receive a strengthening exercise protocol for lower limb muscles. A blind investigator will assess the patients before and immediately after, 3 months and 6 months following the interventions. The main outcomes will be pain, function, physical performance and strength.

Study Timeline

• Study Start: 2014-08
• Study First Submitted: 2014-11-08
• Study First Submitted QC: 2014-11-17
• Study First Posted: 2014-11-20
• Primary Completion: 2015-10
• Study Completion: 2015-11
• Status Verified: 2016-07
• Last Update Submitted: 2016-07-31
• Last Update Posted: 2016-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• Moderate knee osteoarthritis (grade 2 or 3 using the Kellgren-Lawrence radiograph classification), diagnosed based on clinical and radiological criteria of the American College of Rheumatology
• No other lower limb and spine musculoskeletal disorders
• Independent gait
• Body mass index below 32
• Minimum of 4 points in the pain numeric rating scale during climb and descend stairs activities

Exclusion Criteria

• Cognitive or psychological disorders
• Neurological disorders
• History of post-traumatic knee osteoarthritis
• Knee pain at least 12 months
• Prior surgery of the lower limbs or spine
• Fibromyalgia
• Rheumatoid arthritis
• Cardiovascular disease
• Participating in exercise programs and received treatment for the knee at least 3 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Water-based exercises	water-based exercises	Water-based muscle strengthening exercises protocol
Land-based exercises	land-based exercises	Land-based muscle strengthening exercises protocol

Primary Outcome Measures

Name	Time	Method
Function	8 weeks	Pain and Function scores on the Western Ontario and Mcmaster Universities Osteoarthritis Index (WOMAC questionnaire)

Secondary Outcome Measures

Name	Time	Method
Physical Performance	8 weeks	Physical Performance scores on the Timed Up and GO test (TUG)
Lower Limbs Function	8 weeks	Function Scores on the Lower Extremity Functional Scale (LEFS)
Strength muscle	8 weeks	Strength muscle scores measured by heldheld dynamometer
Pain	8 weeks	Pain Scores on the Numeric Pain Rating Scale

Trial Locations

Locations (1)

Universidade Nove de Julho; 🇧🇷 São Paulo, SP, Brazil