Effects of rehabilitation using Nintendo Wii® combined with conventional exercises for upper limbs and cognition in patients with Multiple Sclerosis
- Conditions
- pper ExtremityMultiple SclerosisC20.111.258.250.500
- Registration Number
- RBR-77npcd8
- Lead Sponsor
- niversidade de Brasília
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion criteria will be age under 75 and over 18 years old; diagnosis of Multiple Sclerosis confirmed by a neurologist according to the McDonald criteria, with more than two years of evolution; a score between 3.5 and 6.5 on the Expanded Kurtzke Disability Status Scale (EDSS); no outbreaks in the last 6 months, before the start of the study; presence of mild to moderate cognitive impairment with a minimum score of 18 points on the Montreal Cognitive Assessment; absence of depression, considering the Beck Depression Inventory test, with a score of up to 13 points.
Exclusion criteria will be the presence of illnesses such as psychiatric, other neurological diseases or musculoskeletal disorders that may impede training; be using a course of steroids, whether orally or intravenously, in the last six months prior to the evaluation; be undergoing treatment with botulinum toxin on the date the clinical trial begins or in the six months before the start of the study.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is expected to find an improvement in manual dexterity verified through the Nine hole peg test and the Box in block test, based on a reduction greater than 10% in the execution time in the pre and post test measurements in the experimental group; no difference is expected in handgrip strength verified by the handgrip test, with a difference of less than 5% from pre- to post-test in both groups; and improvement of functional activities verified by the Testd’ Evaluation de la performance des Membres Supérieurs des Personnes Âgées, based on a reduction greater than 5% in execution time.
- Secondary Outcome Measures
Name Time Method An increase in processing speed, improvement in working memory and visuospatial skills is expected, as evidenced by higher scores on the Symbol Digit Modalities Test, Digit Span, California Verbal Learning Test–2nd ed and Rey-Osterrieth Complex Figure Test-A, with a variation of more than 5% between the pre- and post-test.