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临床试验/CTRI/2025/09/094397
CTRI/2025/09/094397尚未招募1/2 期

Comparison of Ultrasound guided Quadratus Lumborum block and Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy

未提供1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年9月18日最近更新:

试验速览

阶段
1/2 期
状态
尚未招募
入组人数
50
试验地点
1
主要终点
To compare the post operative analgesic requirement in patients who received Ultrasoumd guided Quadratus lumborum block and Transverse abdominis plane block after laparoscopic cholecystectomy.

研究概览

简要总结

prospective, double-blinded , interventional study comparing the analgesic efficacy of 2 regional analgesia techniques- posterior Quadratus lumborum block( group 2) and subcostal TAP block(group 1) in patients undergoing laparoscopic cholecystectomy under general anaesthesia. This study aims to evaluate the post operative analgesia provided by the 2 blocks by evaluating the Visual Analogue Scale(VAS) score at fixed time intervals(0 , 6 ,12 and 24hours) , the timing of the first rescue analgesia and total 24hour analgesic consumption. a total of 50 patients (25/ group) will be assigned among the two groups and ultrasound guided blocks will be given with 20ml 0.2% Ropivacaine + 4mg Dexamethasone. the study hypothesises that Quadratus lumborum block provides more analgesia than subcostal TAP block as it can extend upto the thoracic paravertebral space or the toracolumbar space. hence the findings from this study can be used to plan post operative analgesia in laparoscopic cholecystectomy patients

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients posted for elective laparoscopic cholecystectomy surgeries
  • American Society of Anaesthesiologists (ASA) class I, II patients.

排除标准

  • Patient refusal.
  • Bleeding or coagulation abnormality.
  • Local skin infection and sepsis at site of the block
  • Allergy/ Hypersensitivity to the study drugs
  • If laparoscopic cholecystectomy is converted into open cholecystectomy.

结局指标

主要结局

To compare the post operative analgesic requirement in patients who received Ultrasoumd guided Quadratus lumborum block and Transverse abdominis plane block after laparoscopic cholecystectomy.

时间窗: every 6hrs for the first 24hrs post operatively

次要结局

  • 1.Post operative Visual Analogue scale (VAS score) at 0, 6 , 12 and 24 hrs(2.Time taken to request for first dose of rescue analgesia by the patient)

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

Dr. Vridhi Rajan

Dr. B R AMBEDKAR MEDICAL COLLEGE AND HOSPITAL

研究点 (1)

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