Phase 3 clinical study of RM-003 in patients with homocystinuria

Phase 3

• Conditions: Homocystinuria, described as the following cases; cystathionine beta-synthase deficiency(CBS), 5,10-methylenetetrahydrofolate reductase deficiency, defects in cobalamin metabolism

• Registration Number: JPRN-jRCT2080221773
• Lead Sponsor: ReqMed Company, Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04-20
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Sex: All
• Target Recruitment: 8

Inclusion Criteria

Homocystinuria, described as the following cases
- cystathionine beta-synthase deficiency(CBS)
- 5,10-methylenetetrahydrofolate reductase deficiency
- defects in cobalamin metabolism

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma total homocysteine levels at the end of the treatment

Secondary Outcome Measures

Name	Time	Method
Plasma total homocysteine levels at each visit of the treatment<br><br>Plasma homocystine levels at the end of the treatment