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To Establish a Blood Transfusion Prediction Model for Liver Transplantation Patients Based on PBM

Conditions
Blood Transfusion Complication
Interventions
Procedure: Liver transplant
Registration Number
NCT03814772
Lead Sponsor
The Third Xiangya Hospital of Central South University
Brief Summary

Based on the principle of patient blood management, this study aims to reduce the risk of blood transfusion in allogeneic liver transplantation patients, to ensure the safety of blood transfusion, and to provide new methods and basis for restrictive blood transfusion.

Detailed Description

1. Preoperative variables and statistical analysis of a large number of intraoperative blood transfusions in allogeneic liver transplantation patients were performed to screen preoperative variables.

2. Models were established by machine learning algorithms to predict a large number of blood transfusions during surgery, providing a reference for preoperative blood preparation and postoperative outcome.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
2000
Inclusion Criteria
  • 48h preoperative biochemical indicators, blood general indicators, coagulation test complete
Exclusion Criteria
    1. Inspection information is not detailed 2. Blood transfusion information is not detailed 3.Postoperative medical record information is not detailed

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Liver transplantLiver transplant1. 18 years to 65 2. 48h preoperative biochemical indicators, blood general indicators, coagulation test complete
Primary Outcome Measures
NameTimeMethod
one year mortality2019-2021

All-cause mortality

Secondary Outcome Measures
NameTimeMethod
Intraoperative blood transfusion2019-2021

Intraoperative blood component input

Trial Locations

Locations (1)

the Third Xiangya Hospital of Central South University

🇨🇳

Changsha, Hunan, China

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