NCT07695857已完成不适用
Adropin Levels in GCF and Serum of Periodontitis Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1. Adropin levels
研究概览
简要总结
This study aimed to evaluate gingival crevicular fluid (GCF) and serum levels of Adropin and tumor necrosis factor (TNF)-alfa in patients with periodontitis before and after non-surgical periodontal therapy.
详细描述
Thirty periodontitis and thirty periodontally healthy individuals were enrolled in the study. Clinical periodontal measurements were recorded; periodontitis patients received non-surgical periodontal treatment, and GCF and serum samples were collected at baseline and at 6 weeks after treatment. Adropin and TNF-alfa were determined by ELISA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 27 Years 至 49 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •having at least 20 natural teeth, excluding third molars
- •having no systemic disease
- •non-smokers
- •Diagnosed with periodontally health and periodontitis patients
排除标准
- •having any systemic diseases
- •current pregnancy or lactation
- •a history of periodontal treatment in the past 6 months
- •using antibiotic, anti-inflammatory drugs or any other drugs within the past 6 months.
结局指标
主要结局
1. Adropin levels
时间窗: Baseline and at 6 weeks after therapy
Changes in Adropin levels before and after periodontal therapy
次要结局
- TNF-alfa levels(baseline and at 6 weeks after therapy)
研究者
Zeynep Pınar Yucel
Assoc. Prof., DDS, PhD
Giresun University
研究点 (1)
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