Transcranial Magnetic Stimulation ( rTMS ) add-on therapy to Standard treatment in Multiple sclerosis Patients with Depression Symptoms
Phase 2
- Conditions
- Multiple Sclerosis.Demyelinating diseases of the central nervous system
- Registration Number
- IRCT20160523028008N11
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Satisfaction to participate in the study
Patient with multiple sclerosis of any type and with moderate and high depression
Not receive repeated transcranial magnetic stimulation and electroconvulsive therapy in the past two months
Exclusion Criteria
Having a shunt and any other metal object near the head
Interferon consumption
Pregnant or lactating women
Patients at risk of suicide
Patients with other psychiatric disorders such as bipolar disorder
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression rate. Timepoint: before and after 10 sessions of intervention. Method of measurement: Montgomery-Asberg Depression Rating Scale (MADRS).;Fatigue severity test. Timepoint: before and after 10 sessions of intervention. Method of measurement: Fatigue Severity Scale.;Expanded Disability Status Scale. Timepoint: before and after 10 sessions of intervention. Method of measurement: Expanded Disability Status Scale.;Cognitive Assessment. Timepoint: before and after 10 sessions of intervention. Method of measurement: Montreal Cognitive Assessment.
- Secondary Outcome Measures
Name Time Method