Language in Primary Progressive Aphasia
- Conditions
- Primary Progressive Aphasia
- Registration Number
- NCT00537004
- Lead Sponsor
- Northwestern University
- Brief Summary
The purpose of this study is to further define the neurological and linguistic deterioration in primary progressive aphasia.
- Detailed Description
The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral, anatomical and physiological changes in people with PPA throughout the course of the illness. The researchers in this study want to increase awareness of PPA, educate others about this unique disorder, and to encourage more research to eventually develop therapies.
During the three-day research program, participants will be asked to undergo neuropsychological testing (paper and pencil tests that evaluate cognition), advanced imaging (MRI and PET), cognitive experiments, and other computer and language testing batteries. Participants may be asked to return every two years to complete the same measures.
For participants not living near Chicago, IL, flights and accommodations (for both the person with PPA and their companion) will be covered by the study.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 500
- Diagnosis of primary progressive aphasia
- Right-handed
- Native English speaker
- Visual acuity of 20/30 corrected
- Adequate hearing to follow conversation
- Safe for an MRI scan
- Left-handedness
- Claustrophobia
- Presence of significant medical illness that initially or in the future could interfere with continued participation in the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Neuropsychological variables Immediately after testing and at two years post-testing
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Northwestern University
🇺🇸Chicago, Illinois, United States