Comparision of Two Different Feeding Method in Preterms

Not Applicable

• Conditions: Enteral Feeding Intolerance
• Interventions: Other: bolus/intermittant feeding

• Registration Number: NCT05265143
• Lead Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital

Brief Summary

achievement of optimal postnatal growth by adequate enteral nutrition in critically ill preterm infants is a challenge of NICU. signs like abdominal distension, reflux, vomiting, nec is a factors of discontinuing fedding in preterm. this factors plays a role in decisions about which method of gavage feeding is adopted. we compare two different feeding method to achive less fedding tolerence.

Detailed Description

\<1750 gr, \<33 gw infants will enroll study. exckusion criteria: major congenital anomalies major gis anomalies

The study infants are enrolled within 24 hours of birth and sequently randomized to either intermitten feeding (IF) and bolus feeding (BF). Intermittent feeding is defined as delivering enteral nutrition and generally giving 60 min and 2 hours no feeding. this circle repeats 8 times in 24 hours. Bolus feeding is the amount of nutrition put into the syringe was kept 10 cm above the baby and the fluidity was obtained by gravity through the orogastric tube. The data of the patients such as feeding intolerance (gastric residual volume more than %50 of the previous feeding volume, gastric regurgitation, abdominal distension and/or emesis ), whether there is a week-by-week feeding intolerance were noted, NEC, time to reached birth weight, time to achieved full enteral feeding, every 5 minutes during feeding, saturation, respiratory rate and heart rates will record.

Study Timeline

• Study Start: 2015-01-01
• Status Verified: 2022-02
• Study First Submitted: 2022-02-09
• Study First Submitted QC: 2022-03-02
• Last Update Submitted: 2022-03-02
• Study First Posted: 2022-03-03
• Last Update Posted: 2022-03-03
• Primary Completion: 2022-06-01
• Study Completion: 2022-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• <1750 gr preterm infants
• <33 gw
• admitted to our nicu in first day of life

Exclusion Criteria

major congenital anomalies gis anomalies septic shock exitus in 3 days of life

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
bolus feeding group	bolus/intermittant feeding	In bolus feednig group preterm fed by via gravity drip over a short period, usually 15-20 min. it administrated 8-12 times daily
intermittant feeding group	bolus/intermittant feeding	Intermittant feeding is delivered over a 30-60 min by infusion pump. it administrated 8-12 times daily

Primary Outcome Measures

Name	Time	Method
rate of feeding intolerence	1 month	The effect of two different gavage tube feeding methods on feeding intolerance

Secondary Outcome Measures

Name	Time	Method
time to reach full enteral feeding	1 month	The effect of two different gavage tube feeding methods on time to reach full enteral feeding

Trial Locations

Locations (1)

Ümraniye Teaching Hospital; 🇹🇷 Istanbul, Turkey