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Clinical Trials/NCT05063266
NCT05063266
Completed
Not Applicable

Effects of Inspiratory Muscle Training in Pulmonary Hypertensive Patient

Riphah International University1 site in 1 country18 target enrollmentOctober 13, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Inspiratory Muscle Training
Sponsor
Riphah International University
Enrollment
18
Locations
1
Primary Endpoint
6-min walk test (6 MWT)
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Although the progressive nature of pulmonary hypertension (PH), including the impairment of respiratory muscle function, studies have demonstrated beneficial effects of physical exercise on the functional limitations caused by the disease in this population, being an important collaborator to the conventional drug therapy.Respiratory muscle training (RMT) improves functional capacity and quality of life (QoL) in patients.A randomized controlled trial was conducted to evaluate the effectiveness of this protocol on respiratory muscle strength and endurance, functional capacity. 18 subjects were allocated in 2 groups, group A was control group and group B was experimental group. Group A or Control group received deep breathing exercises. Group B received 30 minutes of IMT 6days weekly for 2 weeks by using a pressure threshold device. The purpose of this study was to investigate the effects of inspiratory muscle training (IMT) in PAH. To evaluate effectiveness of IMT mouth pressure device ,functional capacity using 6 minute walking test (6MWT)health assessment via SF 36 questionnaire were used before and after training protocol.

Registry
clinicaltrials.gov
Start Date
October 13, 2020
End Date
July 15, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age group of 40 to 70 years.
  • Both male and females will be included.
  • Patients with a diagnosis of PH (PAPm ≥ 25mmHg and PAOP \<15mmHg);
  • Clinically stable with augmented and unchanged daily medication therapy in the last three months; Subjects who agree to contribute in the research by signing a free and knowledgeable consent form.

Exclusion Criteria

  • Severe ischemic heart disease
  • Left heart failure;
  • Cor pulmonale
  • Cognitive disorders;
  • Orthopedic problems; e.g;fracture in thoracic region.
  • Emergency or elective surgical intervention during the protocol;
  • Recent viral infections;

Outcomes

Primary Outcomes

6-min walk test (6 MWT)

Time Frame: 2nd week

The 6-min walk test (6 MWT) is a submaximal exercise test drive that includes measurement of distance walked throughout a period of 6 minutes. The 6-minute walk distance (6 MWD) stipulates a measure for collective global retort of multiple cardiopulmonary and musculoskeletal structures involved in workout.The 6 MWT provides information about functional capacity, response to rehabilitation and prognosis slanting a broad range of chronic cardiopulmonary situations. Main strengths of the 6 MWT curb from its simplicity in conception and performing, low cost, ease of consistency, and acceptance by test individuals, including those who are deconditioned, aged, or fragile.

SF 36

Time Frame: 2nd week

SF-36 is a setting of universal, clear, and easily instructed quality-of-life methods. These measures hang on upon patient self-reporting and are now widely utilized by trained care groups and by Medicare for everyday observing and assessment of care findings in mature patient role

Study Sites (1)

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