Computerised cognitive behavioural therapy for treatment of depression in multiple sclerosis (MS) (CoSMoS): Clinical trial pilot study

niversity of Sheffield (UK)0 sites24 target enrollmentOctober 6, 2008

Overview

Registry

who.int

Start Date

October 6, 2008

End Date

January 31, 2010

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of Sheffield (UK)

•1\. Aged 18\+, both males and females
•2\. Diagnosis of MS confirmed by neurologist
•3\. Beck Depression Inventory\-II score of at least 14 on two consecutive occasions
•4\. Not currently or within past three months receiving any treatment from a psychologist, psychotherapist or psychiatrist
•5\. Willingness to be randomised to CCBT, at home or primary care facility or treatment as usual

•1\. Unable to read or write English
•2\. Beck Depression Inventory score of at least 29 on two consecutive occasions
•3\. Active suicidal ideas
•4\. Current or life\-time diagnosis of any of the following:
•4\.1\. Psychosis
•4\.2\. Organic mental disorder
•4\.3\. Alcohol or drug dependency
•5\. Kurtzke Expanded Disability Status Scale (EDSS) score of 8\.5 or above
•6\. Unable to use the CCBT package due to physical disability
•7\. Unable to use the CCBT package due to cognitive symptoms (mini\-mental state of 20 below or if, in the opinion of the study psychologist, the individual would be unlikely to benefit from CCBT)