Effect of Intrapulpal Injections on the Post-endodontic Pain in Patients With Symptomatic Irreversible Pulpitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- Post-endodontic pain using a visual analouge scale (VAS)
研究概览
简要总结
To achieve painless treatment in patients with a failed primary IANB, supplementary anesthesia has been advised. The majority of the studies evaluating intrapulpal injections have been performed on asymptomatic teeth. Very limited research has been dedicated to the evaluation of different variables in intrapulpal injections in patients with symptomatic irreversible pulpitis. The aim of this study was to evaluate postoperative pain after an intrapulpal anesthesia injection given after a failed inferior alveolar nerve block (IANB), in patients with symptomatic irreversible pulpitis. This prospective, randomized, double-blind clinical trial was carried out at the Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia. One hundred and eight adult patients, with symptomatic irreversible pulpits in a mandibular first or second molar received an initial IANB with 2% lidocaine. Pain during the endodontic treatment was assessed using a visual analog scale (VAS). Patients experiencing pain on endodontic intervention were randomly allocated to one of the two treatment groups: one group received a supplementary intrapulpal injection while the other received a supplementary intraligamentary injection The presence of postoperative pain was assessed at 1, 2, 3, and 7 days after treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Symptomatic carious exposed mandibular first or second molars.
- •Positive and prolonged response to thermal sensitivity tests and electric pulp tests.
- •Vital coronal pulp on access cavity preparation.
- •American Society of Anesthesiologists class I or II medical history.
- •Ability to understand the use of pain scales.
排除标准
- •Active pain in more than 1 tooth.
- •Teeth with fused roots.
- •Radiographic evidence of an extra root.
- •Large restorations with overhanging margins.
- •Full crowns or deep periodontal pockets.
- •Known allergy or contraindications to any content of the local anesthetic solution or NSAIDs
- •History of known or suspected drug abuse.
- •Taking any drugs which could affect the pain perception, e.g, opiods, antidepressants, anticonvulsants, muscle relaxants, anxiolytics, sedatives, nsaids. 23
- •Pregnant or breastfeeding patients.
- •Patients with asthma, gastric ulcers, and bleeding disorders.
研究组 & 干预措施
Supplementary Intrapulpal injection
Supplementary Intrapulpal injections were given using a 30-gauze needle with sufficient back pressure.
干预措施: Supplementary anesthetic injections (Procedure)
Intraligamentary injection
Intraligamentary injections were given using an intraligamentary syringe with back-pressure after a failed primary inferior alveolar nerve block.
干预措施: Supplementary anesthetic injections (Procedure)
结局指标
主要结局
Post-endodontic pain using a visual analouge scale (VAS)
时间窗: 6hours, 1 day, 3 days, 7 days
Evaluation of numerical visual analouge pain scores after the completion of root canal treatment. The scale was 170mm long and the the values were continous and numerical. The 0 indicates no pain and 170 indicates the maximum possible pain
次要结局
未报告次要终点
研究者
Dr. Vivek Aggarwal
Professor
Jamia Millia Islamia