The multicenter randomized controlled study for Qihuang yishen granule improve proteinuria of diabetic kidney disease
- Conditions
- Diabetic kidney disease
- Registration Number
- ITMCTR1900002263
- Lead Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
? meet the Western diagnostic criteria of Diabetic kidney disease and diagnostic criteria for TCM syndromes;
? age 30 to 75 years (including 30 and 75 years);
? 24h urine protein quantification between 0.5 ~ 3.5g, eGFR30 ~ 90ml/min;
? after antihypertensive treatment, the blood pressure is controlled at =140/90mmHg;
? the blood sugar is stable, and the glycated hemoglobin is below 8%;
? signed informed consent, outpatient and inpatients who can be followed up for a long time.
? blood pressure <90/60mmHg;
? patients with blood creatinine increased to 2 times in the past six months;
? unilateral or bilateral renal artery stenosis;
? other serious diabetic complications and severe macrovascular events in the past six months, such as cerebral hemorrhage, large-area cerebral infarction, acute myocardial infarction;
? patients with various infectious diseases in the past 4 weeks;
? combined with other serious diseases, such as blood system diseases, malignant tumors, etc.;
? serious psychological or mental abnormalities;
? pregnant or lactating women.
Note: Any item that meets the above conditions will not be included in this study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24-hour urine protein quantitation;
- Secondary Outcome Measures
Name Time Method fasting plasma glucose;Urinary microalbumin creatinine ratio;blood lipoid;glycosylated hemoglobin;renal function;