Effectiveness of a Buteyko-based Breathing Technique on Psycho-physiological Parameters of Adults With Asthma - a Randomized, Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 63
- 试验地点
- 2
- 主要终点
- Change in Endtidal CO2
研究概览
简要总结
The purpose of this study is to investigate the effects of a Buteyko-based breathing technique on physiological and psychological parameters in adults with asthma
详细描述
The investigators explore the effects of a Buteyko-based breathing technique training using a treatment group vs. control group design and a repeated measures design with follow-up measurements 3 and 6 months after the intervention. The sample size calculation was made for an effect of d = .20 with repeated measures, a power of 1- β = .80 and α = .05. Additionally the investigators plan to take measurements (only once) from healthy volunteers matching them (age and gender) with the asthma patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Written informed consent, regular intake of prescribed asthma medication according to the AWMF scheme level 1, native speaker of german
排除标准
- •Participation in another study, comorbidities (heart diseases, cancer still under treatment, psychiatric diseases)
研究组 & 干预措施
Buteyko Training
Breathing exercises according to the Buteyko Breathing Technique
干预措施: Buteyko Breathing Technique (Other)
Control Group
Standard care as usual
结局指标
主要结局
Change in Endtidal CO2
时间窗: Between baseline and 3 month follow up
Capnometry
Change in Nijmegen-Score
时间窗: Between baseline and 3 month follow up
Questionnare assessing hyperventilation
Change in Buteyko CP
时间窗: Between baseline and 3 month follow up
Breath hold test
次要结局
- Spirometry: FEV1(Between baseline and 6 month follow up)
- Spirometry: FEV1/VCin(Between baseline and 6 month follow up)
- Spirometry: PEF(Between baseline and 6 month follow up)
- Heart Rate Variability (SDNN)(Between baseline and 6 month follow up)
- Heart Rate Variability (RMSSD)(Between baseline and 6 month follow up)
- Heart Rate Variability (LF/HF)(Between baseline and 6 month follow up)
- Vascular stiffness(Between baseline and 6 month follow up)
- Blood Pressure(Between baseline and 6 month follow up)
- Haemodynamics Stroke volume(Between baseline and 6 month follow up)
- Haemodynamics Cardiac output(Between baseline and 6 month follow up)
- Haemodynamics Total Vascular Resistance(Between baseline and 6 month follow up)
- Haemodynamics Cardiac index(Between baseline and 6 month follow up)
- Haemodynamics Perfusion(Between baseline and 6 month follow up)
- Haemodynamics Plethvariability(Between baseline and 6 month follow up)
- Oxygen Saturation(Between baseline and 6 month follow up)
- ACQ(Between baseline and 6 month follow up)
- AQLQ(Between baseline and 6 month follow up)
- ARCIM Questionnaire(Between baseline and 6 month follow up)
- STAI Questionnaire(Between baseline and 6 month follow up)
- ASF Questionnaire(Between baseline and 6 month follow up)
- Asthma medication(Between baseline and 6 month follow up)