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临床试验/NCT05281705
NCT05281705Unknown不适用

Feasibility@ 48: A Cross Sectional Multi-centre Study of Intensive Care Unit (ICU) Mobility Practices Across the United Kingdom.

University College, London1 个研究点 分布在 1 个国家目标入组 750 人开始时间: 2022年3月3日最近更新:
适应症

试验速览

阶段
不适用
入组人数
750
试验地点
1
主要终点
The proportion of patients achieving a ICU mobility scale more than 3 on the day of the study

研究概览

简要总结

Intensive Care Unit (ICU) patients commonly experience muscle loss at a rate of 2-3% day. Traditionally, critically ill patients have been managed in bed, however current research suggests that prolonged bedrest cause mechanical silencing of the muscles and exacerbates this muscle wasting. This ICU acquired weakness (ICUAW) leads to poor functional outcome and higher mortality. Research suggests that early out-of-bed mobilisation should occur within 48-hours of ICU admission to militate against this risk, however, this is only achieved in 30% of cases. Common barriers to mobilisation are unstable blood pressure, ventilation, sedation and fatigue. It is plausible that 48-hours is an unrealistic timeframe for mobilisation.

The aim of this study is to explore the mobility practices on a given day in UK adult ICUs. The objectives are to:

  1. Determine the level of mobility that is achieved by each patient on adult ICUs, on a given day in the UK.
  2. Determine the typical physiological profile of patients on ICU that are both able and unable to participate in antigravity exercise
  3. Determine the proportion of adult ICU admissions that achieve out of bed mobilisation in the first 48-72 hours
  4. Explore clinician decision making about mobilisation

This is a multi-centre cross-sectional study on one-day only. Over a 24-hour period data will be collected for all ICU patients at the participating centres. The lead physiotherapist will record the highest level of mobility achieved that day, and the physiological parameters from clinical observations. The reasons for the level of mobility achieved will be ranked in order of importance. These data are routinely collected. Data will be anonymised.

Data will be analysed to determine feasibility of mobilisation at 48hours and develop a flow diagram of mobilisation decision-making.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •All patients who are admitted to a participating ICU on the study day will be included

排除标准

  • 未提供

结局指标

主要结局

The proportion of patients achieving a ICU mobility scale more than 3 on the day of the study

时间窗: Day 1

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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