Impact of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance on Prognosis for ST-segment Elevation Myocardial Infarction

Completed

• Conditions: ST Elevation (STEMI) Myocardial Infarction

• Registration Number: NCT06759532
• Lead Sponsor: Chinese PLA General Hospital

Brief Summary

The aims of the study were to evaluate the predictive value of persistent microvascular obstruction (MVO) by cardiac magnetic resonance for main adverse cardiac events in ST-segment elevation myocardial infarction patients.

MVO in the acute phase of myocardial infarction has been considered to be strong predictor of a poor prognosis. We plan to explore the relationship between persistent MVO and the long-term prognosis of patients with STEMI. We made hypothesis that patients with persistent MVO have a poor prognosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-04-01
• Primary Completion: 2024-07-20
• Study Completion: 2024-10-20
• Status Verified: 2024-12
• Study First Submitted: 2024-12-30
• Study First Submitted QC: 2024-12-30
• Last Update Submitted: 2024-12-30
• Study First Posted: 2025-01-06
• Last Update Posted: 2025-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 344

Inclusion Criteria

• ST-segment elevation myocardial infarction undewent primary percutaneous coronary intervention

Exclusion Criteria

• contraindications for cardiac magnetic resonance
• severe heart failure
• previous myocardial infarction.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main aderverse cardiac events	5 years after myocardiac infarction	Composite endpoint of all-cause death, readmission due to heart failure, recurrent myocardial infarction, and unexpected vascularization.

Trial Locations

Locations (1)

Chinese PLA general hospital; 🇨🇳 Beijing, Beijing, China