An Algorithm for Intra-operative Goal-directed Haemodynamic Management in Non-cardiac Surgery

Completed

• Conditions: Fracture of Surgical Neck of Humerus; Colonic Tumor; Stage IIIB Ovarian Carcinoma; Neoplasm of Head of Pancreas

• Registration Number: NCT01384097
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

A systematic literature search a goal-directed haemodynamic algorithm was created. The hypothesis of this study was that the goal-directed haemodynamic algorithm is feasible and can improve clinical outcome.

Detailed Description

After a systematic literature search a goal-directed haemodynamic algorithm was created. The algorithm was adapted to international standards and consensus was reached through a modified Delphi method at international meetings. The feasibility of using the algorithm for intraoperative haemodynamic management was tested and the resultant clinical data analyzed retrospectively for several types of surgery with the hypothesis that the goal-directed haemodynamic algorithm is feasible in the clinical setting and can improve clinical outcome.

Study Timeline

• Study Start: 2007-09
• Primary Completion: 2011-02
• Study Completion: 2011-06
• Study First Submitted: 2011-06-27
• Study First Submitted QC: 2011-06-27
• Study First Posted: 2011-06-28
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-07
• Last Update Posted: 2011-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 774

Inclusion Criteria

• Patients undergoing a surgical repair of hip fractures, open right hemicolectomy and extended hemicolectomy, radical tumor debulking in primary ovarian cancer or a pylorus-preserving pancreatic head resection at the Charité - University Medicine Berlin, Campus Virchow Clinic
• 18 years and older

Exclusion Criteria

• emergency procedures

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
hospital length of stay	a period of 60 days	The perioperative hospital length of stay is assessed.

Secondary Outcome Measures

Name	Time	Method
need for ventilator therapy	a period of 60 days	The perioperative need for ventilator therapy is assessed.
monetary reimbursement for prolonged hospital stay	a period of 60 days	The monetary reimbursement for prolonged hospital stay is assessed to evaluate the impact on financial consequences.

Trial Locations

Locations (1)

Charité - University Medicine Berlin; 🇩🇪 Berlin, Germany