The evaluation and comparison of Coronary sinus Inflammatory and ischemic biomarkers level in retrograde-anterograde versus anterograde cardioplegia during cardiopulmonary bypass surgery: A single blinded randomized controlled trial
Phase 3
- Conditions
- Myocardial Infarction.myocardial infarction specified as acute or with a stated duration of 4 weeks (28 days) or less from onset
- Registration Number
- IRCT201202048860N1
- Lead Sponsor
- Rajaie cardiovascular medical and research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
all patients undergoing cardiopulmonary bypass surgery at one operator service in our institution were prospectively screened for inclusion in the investigation. Consecutive patients with the following characteristics were selected for inclusion in the study: valvular with at least two vessels coronary disease.
Exclusion criteria: total respiratory disability; renal failure (Cr > 2); age = 80 years old; history of MI in 4 weeks preoperatively; failure to retrograde catheter insertion; where total respiratory disability is any of: height-corrected FEV1 (1.1-1.4) and DLCO less than 30 percent predicted (Technical revisions to medical criteria for determinations of disability).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality. Timepoint: 30-day after surgery. Method of measurement: ID.
- Secondary Outcome Measures
Name Time Method