Exploring the Utility of Non-Invasive Coronary Angiography in Suspected Acute Coronary Syndromes with Low Level Troponin Elevation. (EN-ACT): A national study

Not Applicable

Recruiting

• Conditions: Acute Coronary Syndromes; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12622001316796
• Lead Sponsor: Flinders University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-11
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

Patients presenting to the emergency department will be considered eligible for analysis if they meet all of the following:
a) Age of 18 years or older
b) Presenting with symptoms suggestive of ACS;
c) Troponin elevation above the 99th percentile URL but less than 5x URL
d) Willing and able to give written informed consent.

Exclusion Criteria

Patients presenting to the ED will be considered ineligible for analysis if they meet any of the following:
a) Ongoing chest pain and/or dynamic ST segment changes on ECG;
b) Haemodynamic instability;
c) Known coronary artery disease;
d) High-risk features and/or deemed unsuitable for angiography, including:
i. Renal dysfunction (eGFR less than 60mL/min/1.73m2);
ii. Contrast allergy;
iii. Atrial fibrillation;
iv. Intolerance to beta blockers;
v. Limited life expectancy, dementia or chronic liver disease;
vi. Pregnancy.
e) Reside overseas;
f) Has language barrier preventing informed consent to participate in the trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified