CT-CAG registry
Recruiting
- Conditions
- coronary artery disease
- Registration Number
- NL-OMON24918
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
Patients receiving clinically indicated CCTA, without anginal complaints and without a history of coronary artery disease (i.e. referred for cardiac valve surgery, patients with ventricular tachycardia or reduced left ventricular function)
Exclusion Criteria
- Anginal complaints or acute coronary syndrome
- History of CAD
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Diagnostic yield of using CCTA as gatekeeper for CAG, in patients without history of CAD and without anginal complaints.<br /><br>- Diagnostic agreement of CCTA for the assessment of significant (>50% stenosis) obstructive coronary artery disease, using invasive coronary angiography measurements as the reference standard.<br>
- Secondary Outcome Measures
Name Time Method - The cumulative incidence of myocardial infarction, hospital admission for suspected acute coronary syndrome or unstable angina pectoris, revascularization procedures (PCI, CABG), coronary angiography without revascularization and death, from day 1 to 1 year after procedure.<br /><br>- Evaluation of patient acceptance, measured by a patient acceptance questionnaire.<br /><br>- Cost-effectiveness of using CCTA as gatekeeper for CAG in patients without history of CAD and without anginal complaints.<br /><br>- Cumulative contrast dose from either CCTA and CAG<br /><br>- Cumulative incidence of complications related to CCTA and CAG<br>