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Retinal Nerve Fibres Layers Thickness Study in Glaucomatous Patients

Not Applicable
Completed
Conditions
Glaucoma
Registration Number
NCT01254006
Lead Sponsor
University of Roma La Sapienza
Brief Summary

In this study the investigators are going to study the retinal nerve fibers layers (RNFL) modification of two groups of patients, one taking no drugs, the other taking forskolin, rutin and vitamins B1 and B2.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Age (30-80 years);
  • Baseline Intraocular pressure (IOP) (20-32 mmHg): average untreated Intra Ocular Pressure (IOP) for both eyes as determined from 2 to 4 visits within a 6-months period;
  • Central Corneal Thickness (CCT) (475-650 µm): average of 3 different measurements from both eyes during the same visit;
  • Pattern standard deviation (PSD) (0,50-3,00 dB) average of both eyes as stated on the most recent visual field index report
  • Vertical Cup/Disk ratio (0,00-0,80): average of both eyes
  • All these data were entered into a calculator specially designed for STAR (Scoring Tool for assessing risk) II parameter. The patients were divided into low-, moderate- and high risk groups according to the result given by the calculator.
Exclusion Criteria

-other ocular pathologies than glaucoma

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
retinal nerve fibres layer thickness
Secondary Outcome Measures
NameTimeMethod
global risk threshold for glaucoma progression

Trial Locations

Locations (1)

Univerisity La Sapienza

🇮🇹

Latina, Italy

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