Correlation between the damage to structure and function in primary open angle glaucoma.
- Conditions
- Health Condition 1: null- PRIMARY OPEN ANGLE GLAUCOMA
- Registration Number
- CTRI/2014/05/004614
- Lead Sponsor
- VASAN EYE CARE HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 200
•Subjects visiting a glaucoma clinic diagnosed with primary open â?? angle glaucoma.
•Subjects should have best corrected visual acuity not less than 6/18.
•Refractive spherical error within the range of -6.00DS to + 3.00 DS and cylindrical error within +/- 2.5D.
•Visual fields examination of the subjects demonstrating field defects secondary to glaucomatous damage with mean deviation ranging from -2 to -10 decibels (db).
•The visual fields of the subjects should be within the reliability criteria ( <20% fixation losses, false positives and false negatives).
•The signal to noise ratio for a reliable OCT â?? RNFL scan shall not be less than 6.
•History of(H/O) retinal disease or photocoagulation.
•H/O ocular trauma or surgery except an uncomplicated cataract surgery.
•H/O other optic nerve disease except glaucoma
•H/O amblyopia
•Neurological disease which can affect visual fields.
•Visually significant cataracts (Posterior Subcapsular Cataracts, > N.S Grade II).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Structure - function correlation in early and moderate open â?? angle glaucoma with regards to RNFL thickness and visual field indices.Timepoint: At time of presentation over the glaucoma outpatient department
- Secondary Outcome Measures
Name Time Method Pattern of visual field loss and retinal nerve fibre layer changes in early and moderate primary open angle glaucoma.Timepoint: At time of presentation to the glaucoma outpatient department.