Macular Retinal Thickness and Retinal Nerve Fiber Layer Thickness Measured in Amblyopia, an OCT study.
- Conditions
- amblyopialazy eye10047060
- Registration Number
- NL-OMON31038
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 130
*diagnosed amblyopia caused by an anisometropia, strabismus or a combination of these two who received therapy with a visual acuity difference of two lines between the two eyes.
*The patient has to be at least three years old and cooperative enough to sit through all examination, including the OCT examination.
*Refractive error within the range of S+12.0 and S-12.0 due to the limitations of the OCT device.
*A patient needs to have at least a 2 diopter spherical difference in refraction between both eyes and/or a 2 diopter astigmatic difference to be part of the anisometropic group.
*Patients with any manifest ocular deviation or eccentric fixation will be included in the strabismic group.
*To be part of the normal group, the patient needs to have a straight eye position, but phorias are allowed. The refraction needs to be similar in both eyes and should not be above S+5.0 or S-8.0, astigmatism should not exceed 2 diopters
*Patients with a history of organic eye diseases or a history of intraocular surgery.
*Patients with a history of cataract or existing cataract
*Patients with retinal disorders, glaucoma or laser treatment in the preceding years.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>* Visus<br /><br>* Etiology amblyopia<br /><br>* OCT measurements (outlined in appendix C of the protocol)</p><br>
- Secondary Outcome Measures
Name Time Method <p>* Refraction<br /><br>* Stereopsis<br /><br>* As-length<br /><br>* Age</p><br>