Change in retinal nerve fiber layer thickness after optic disc hemorrhage in non glaucomatous patients

Recruiting

• Conditions: Optic disc hemorrhage in patients with glaucoma requires intensive lower targer intraocular pressure(IOP); Optic disc hemorrhage; Retinal nerve fiber layer thickness; Glaucoma progression

• Registration Number: TCTR20210201007
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-01
• Study Completion: 2021-03-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

1. Age over 18 years old
2. Optic disc hemorrhage was detected and documented by fundus examination or fundus photograph
3. Optical Coherence Tomography of RNFL and GCA was obtained at 0,12 months after optic disc hemorrhage

Exclusion Criteria

1. BCVA 0.4 logMar or worsen
2. Spherical equivalent Refractive error more than 8.00D or -8.00D
3. Presence of concurrent retinal disease such as retinal vascular disease or optic nerve disease that effects visual field interpretation
4. Present of evidence of glaucomatous eye

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Average retinal nerve fiber layer thickness at 12 months after optic disc hemorrhage as micrometer from OCT RNF

Secondary Outcome Measures

Name	Time	Method
Average ganglion cell thickness at 12 months after optic disc hemorrhage as micrometer from OCT GCA,retinal nerve fiber layer thickness each sector at 12 months after optic disc hemorrhage as micrometer from OCT RNFL,Number of patients who progress to glaucoma at 12 months after optic disc hemorrhage Patient was diagnosed glaucoma or treated with IOP lowering drugs,Ganglion cell thickness in each sector at 12 months after optic disc hemorrhage as micrometer from OCT GCA