NL-OMON39386
Completed
Not Applicable
The role of genetic factors in the aetiology of achalasia - Genetics in achalasia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 450
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Diagnosis of idiopathic achalasia confirmed by oesophageal manometry that show the following criteria:
- •\- Aperistalsis or simultaneous contractions in the oesophageal body.
- •\- LOS dysrelaxation.
- •\- Age \*18 years.
- •\- Written informed consent.
Exclusion Criteria
- •\- Having a medical or mental contradictory condition to participate in the study, even after agreeing to participate.
- •\- Pseudoachalasia.
- •\- Upper gastrointestinal malignancy.
- •\- Chagas disease.
- •\- Previous allogeneic bone marrow transplant.
- •\- Non leukocyte depleted whole blood transfusion within 120 days of the date of genetic sample collection.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Study of the genetic causes of disorders of the aorta, arteries and cardiac valvesaortic dilatationheart valve malformation100822061000751010002363NL-OMON39758niversitair Medisch Centrum Sint Radboud500
Not yet recruiting
Not Applicable
Study on genetic factors in the pathogenesis of Inflammatory Bowel Disease: Gathering a matched control populatioCrohns diseaseUlcerative Colitis1001796910003816NL-OMON30241Academisch Medisch Centrum3,000
Completed
Not Applicable
A study to improve our understanding of the genetic causes of swelling in babies before birthFetal oedema/hydrops with a focus on lymphatic related hydropsPregnancy and ChildbirthConditions involving the integument and temperature regulation of fetus and newbornISRCTN22076461St George’s University Hospitals NHS Foundation Trust60
Completed
Not Applicable
Exploratory Study of Genetic Factors Related to the Inhibitory Effect of Tolvaptan on Increased Kidney Volume in Patients with Autosomal Dominant Polycystic Kidney DiseaseAutosomal Dominant Polycystic Kidney DiseaseJPRN-UMIN000031976Otsuka Pharmaceutical Co.,Ltd.890
Recruiting
Not Applicable
The role of exogenous genes in the pathogenesis of human cholestatic liver diseases.Primary biliary cholangitis, Primary sclerosing cholangitis, autoimmune hepatitis, autoimmune liver diseases, cholestatic liver diseasesJPRN-UMIN000029040Department of Gastroenterology, Yamagata University Faculty of Medicine100