Study of the genetic causes of disorders of the aorta, arteries and cardiac valves
Completed
- Conditions
- aortic dilatationheart valve malformation100822061000751010002363
- Registration Number
- NL-OMON39758
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
Inclusion criteria
1. Patients and familymembers with thoracic aortic aneurysm and dissection
2. Patients and familymembers with Marfan syndrome and related conditions
3. Patients and familymembers with bicuspid aortic valve, specifically if associated with aortic aneurysm or history of sudden death or aortic dissection
4. Patients and family members with arterial aneurysms and/or valve abnormalities
No restriction for age or sex.
Exclusion Criteria
None
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Identification of the genetic factors underlying thoracic aortic aneurysms or<br /><br>modify the phenotypic severity.</p><br>
- Secondary Outcome Measures
Name Time Method <p>nvt</p><br>