NL-OMON35523
Recruiting
Not Applicable
Clinical and molecular genetic aspects of idiopathic epilepsies - genetics of idiopathic epilepsies
Epilepsiecentrum Kempenhaeghe0 sites300 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- epilepsy
- Sponsor
- Epilepsiecentrum Kempenhaeghe
- Enrollment
- 300
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with a familial history of epilepsy, with multiple (at least 4\) family members affected
- •2\. Patients with a severe form of epilepsy with onset in the first year of life in which no acquired cause can be detected.
- •3\. patients with a combination of epilepsy, mental retardation and dysmorphia (\=contiguous gene syndrome, probably caused by deletion/duplication of multiple genes and detectable by CGH)
- •4\. Patients on a ketogenic diet with epilepsy of unknown origin
- •Theoretically there are no age restrictions. In case of severe epilepsy with early onset (cfr.2\), cases with neonatal onset will also be included, but as DNA diagnostics in a genetic research setting only will be done after all other possible causes are excluded, inclusion in this study in actual practice will only be done after 2 months of life.
Exclusion Criteria
- •Patients in which a acquired cause of epilepsy is suspected (for example perinatal brain damage, lesions visible on MRI,...)
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Clinical course, outcome and genetics of inherited arrhythmias in childrenA multicenter studyI49.8I49I47.2I45.8Other specified cardiac arrhythmiasOther cardiac arrhythmiasVentricular tachycardiaOther specified conduction disordersDRKS00028138Deutsches Herzzentrum München, Technische Universität München796
Not yet recruiting
Not Applicable
Study on genetic factors in the pathogenesis of Inflammatory Bowel Disease: Gathering a matched control populatioCrohns diseaseUlcerative Colitis1001796910003816NL-OMON30241Academisch Medisch Centrum3,000
Not yet recruiting
Phase 2
Study of PCOS and to know the effect of Shatapushpaa Churna and Yoga therapyHealth Condition 1: O992- Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperiumCTRI/2022/03/041365Department of Vikriti Vigyan Faculty of Ayurveda Institute of Medical Sciences BH
Recruiting
Not Applicable
Elucidating the genetic pathomechanism underlying rare and hereditary kidney diseasesDRKS00008910Institut für HumangenetikUniklinik Köln3,000
Recruiting
Not Applicable
Identification of molecular biomarkers of untreated follicular lymphoma treated by GB therapy.JPRN-jRCT1060200019Maeda Yoshinobu200