Comparative Efficacy of Saccadic and Biofeedback Training in Homonymous Hemianopia

Not Applicable

Not yet recruiting

• Conditions: Hemianopia, Homonymous

• Registration Number: NCT06638619
• Lead Sponsor: University of Alabama at Birmingham

Brief Summary

This pilot study aims to understand how eye movements change in people with vision loss from stroke after completing one of two types of training. The study will look at how eye movements and reading performance change after training. Researchers will compare the results of two groups: one group will complete five clinical training sessions using an eye-tracking machine for 30 minutes each, while the other group will do at-home reading exercises for 20 minutes a day, 5 days a week, for 6 weeks. The goal is to see if there is a difference in performance between the two types of training.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-09-30
• Study First Submitted QC: 2024-10-10
• Study First Posted: 2024-10-15
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-12
• Last Update Posted: 2025-05-15
• Study Start: 2025-06
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Diagnosis of stroke
• Presence of hemianopia with central vision involvement
• Stroke occurred at least 6-months before enrollment

Exclusion Criteria

• Presence of hemianopia with macular sparing
• Diagnosis of hemispatial neglect

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Oculomotor Metrics	Pre-training and at 6-weeks.	Participants will be asked to read aloud a series of sentences presented on a display. Eye movements will be recorded in real-time using an Eye-Link 1000 infrared eye-tracking camera, as the patient is reading what is on the display. The primary outcome measure will be the first saccade landing location.

Secondary Outcome Measures

Name	Time	Method
Pepper Visual Skills Reading Test (VSRST)	Pre-training and at 6-weeks.	A clinical reading assessment used in low vision settings to assess for common patterns of reading errors (misidentifications, skipped letters or words, skipped lines). The participant reads aloud lines of text (random letters and words of increasing complexity and decreasing line spacing.