The effects of probiotics on glycaemic control in Type 2 diabetes mellitus patients

Not Applicable

Recruiting

• Conditions: Type 2 Diabetes Mellitus; Metabolic and Endocrine - Diabetes; Alternative and Complementary Medicine - Other alternative and complementary medicine

• Registration Number: ACTRN12615001135505
• Lead Sponsor: Dr. Neoh Chin Fen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-27
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1) T2DM patients, with glycosylated hemoglobin (HbA1c) of 7% to 10%
2) No change in oral hypoglycaemic agents during the last 3 months

Exclusion Criteria

1.Already on insulin or insulin analogs or maximum dose of oral hypoglycaemic agents
2.Regular intake of probiotics (including fermented dairy products), antacids, H2-receptor blockers, proton pump inhibitors, loperamide, corticosteroids or sex steroids
3.Systemic antibiotics within 1 month before inclusion
4.Active smokers (still smoking at least 1 cigarette for the past 6 months)
5.Daily alcohol consumption >30 g
6.Significant immunodeficiency
7.Liver, thyroid, kidney or cardiac valvular disorder
8.Chronic gastrointestinal disease
9.Neurological disorders (e.g. Alzheimer's disease, stroke, Parkinson disease)
10.Breast-feeding, pregnancy or plan to become pregnant in the next 6-12 months
11.Participation in another clinical trial within the last 6 months
12.Enduring mental health problems (e.g. schizophrenia, bipolar disorder)
13.Incapacity to give consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified