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Clinical Trials/NCT06710301
NCT06710301
Recruiting
Not Applicable

Study of the Cortical Correlates of Spatial Navigation Skills in an Immersive Virtual Reality Environment

IRCCS Eugenio Medea1 site in 1 country70 target enrollmentNovember 14, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebral Palsy (CP)
Sponsor
IRCCS Eugenio Medea
Enrollment
70
Locations
1
Primary Endpoint
Power Spectral Density (PSD)
Status
Recruiting
Last Updated
5 months ago

Overview

Brief Summary

The goal of this study is to investigate the neural mechanisms that undergoes spatial navigation skills in children/adolescents aged between 8 and 17 years. These skills play an important role in daily life, as they allow us to orient ourselves in familiar and unfamiliar environments, locate objects, interact with them and memorize their position. Navigation abilities vary widely between individuals, change with age and might be affected by diseases, such as the cerebral palsy (CP). Previous studies have, in fact, demonstrated differences in the learning and adaptation methods of spatial navigation skills in children affected by CP compared to typically developing (TD) peers. Through the use of the electroencephalogram (EEG) we want to shed light on the mechanisms that govern this ability with the aim of:

  1. better characterize spatial navigation skills in children/adolescents, both TD and affected by CP;
  2. investigate the origin of the differences found between the spatial navigation skills of TD children and those affected by CP, improving knowledge of the pathology and thus allowing, in the future, to identify more adequate rehabilitation interventions.
Registry
clinicaltrials.gov
Start Date
November 14, 2024
End Date
December 31, 2026
Last Updated
5 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
IRCCS Eugenio Medea
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • typically developing subjects aged between 8 and 17 years;
  • subjects with CP aged between 8 and 17 years;

Exclusion Criteria

  • subjects aged under 8 or over 17 years;
  • subjects with epileptic problems;
  • subjects with poor head control;
  • subjects with visual problems that can not be corrected with prescription lens;

Outcomes

Primary Outcomes

Power Spectral Density (PSD)

Time Frame: Once

Differences in power values between TD and CP subjects

Navigation performance

Time Frame: Once

Navigation performance based on the following parameters: number of routes visited in each trial; total length of the path for each trial; error between distance traveled and ideal distance for each trial (identified as the minimum distance to reach the treasure from the starting point); angle of rotation of the viewer in each trial; duration of each trial.

Study Sites (1)

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