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Clinical Trials/NCT06032715
NCT06032715
Recruiting
Not Applicable

Brief Intervention for Reducing Prolonged Use of Sleep Medication Among Elderly

University Hospital, Akershus1 site in 1 country120 target enrollmentOctober 9, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Harmful Use of Hypnotic
Sponsor
University Hospital, Akershus
Enrollment
120
Locations
1
Primary Endpoint
Inappropriate Z-hypnotics use
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Randomized controlled trial to evaluate effectiveness of behavioral Brief Intervention administered by General practitioners (GPs) versus business as usual on use of Z-hypnotics by elderly patients in primary care.

Detailed Description

Two armed study with controlled masked first part over 6 months. Active arm is with Brief Intervention for inappropriate use of Z-hypnotics among elderly with intervention delivered by trained GPs. Control arm is for patients handled by their (non-trained) GPs with business as usual (BAU). Main outcome is 6 weeks after intervention with additional data collection points after 6 months (blinded) and long-term follow-up to 12 months (open). After 6 months there will be an open single crossover as BAU GPs will then also receive training in the Brief Intervention method. Baseline assessments are limited to self reports and automatic sleep assessment with actigraphy to avoid assessment effects. Follow-up at main outcome time point is in person, some outcomes are also by telephone assessment and compared to baseline prior to intervention (e g Actigraphy assessment.

Registry
clinicaltrials.gov
Start Date
October 9, 2023
End Date
June 30, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Akershus
Responsible Party
Principal Investigator
Principal Investigator

Christofer Lundqvist

Professor

University Hospital, Akershus

Eligibility Criteria

Inclusion Criteria

  • Self-reported use of Z-hypnotics \> 4 days per week and \> 4 weeks

Exclusion Criteria

  • diagnosis of dementia,
  • diagnosis of psychosis,
  • diagnosis of major depression,
  • diagnosis of delirium,
  • unable to give informed consent,
  • insufficient Norwegian language capacity to complete tests

Outcomes

Primary Outcomes

Inappropriate Z-hypnotics use

Time Frame: 6 weeks

Proportion of patients with prolonged use of Z-hypnotics

Secondary Outcomes

  • Pain visual analogue scale (VAS)(6 weeks)
  • Change compared to baseline of Z-hypnotics use(6 months)
  • Experience of sleep(6 months)
  • Cognitive function(6 months)
  • Sleep efficiency (random subpopulation)(6 weeks)
  • Inappropriate Z-hypnotics use(baseline)

Study Sites (1)

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