Effect of Indravaruni (Colocynth Citrullus schrad.) in the management of Kampa w.r.t tremors- an open-labelled clinical trial.

DISEASE REVIEW-

By definition tremors are involuntary, oscillatory movements resulting from alternating contraction and relaxation of muscles. Tremors are usually classified according to frequency, amplitude, position and the body part affected.

Physiological tremors are fine, high frequency postural tremor occurring in hyperthyroidism, alcohol withdrawal and adverse effect of beta agonist bronchodilators.

Essential tremor is the most common pathological tremor involving upper limbs (typically similar) head, voice6.

Parkinson’s disease causes slow, pill rolling tremor, worse at rest and reduces with voluntary movements.

Other involuntary movements include-

1.Dystonia- sustained muscle contractions, leading to twisting repetitive movements.

2.Chorea- brief, jerky, random movements.

3.Athetosis- slower, writhing movements

4.Ballism- violent flinging movements

5.Tics- repetitive, stereotyped movements can be briefly suppressed by the patient.

Gatradi chalanam – the one which produces shaking or movements in the body.

Tremors or involuntary movements can be considered as Kampa according to ayurveda.

Acharya charaka has quoted Kampa as one of the nanatmaja vyadhi. Few other acharyas have quoted Kampa as vepathu. Kampa can be considered as a cardinal symptom of vataprakopa and pittakshaya. There is no separate samprapti told for Kampa, so in general samprapti of vata vyadhi8 is considered.

1. Nidana sevana ( vata vardhaka ahara)

2. Rasa dhatu kshaya

3. Utarotta dhatu kshaya

4. Vitiated vata travels throughout the body

5.Vitiated vata impairs the Sneha guna in the srotas by its ruksha, sheeta and laghu guna

6.The vitiation of srotas by vata, impairs the motar functions of the body causing increase in the chala guna.

7. KAMPA

Kampavata can be considered as parkinsons disease. Acharya vagbhata has mentioned Kampa as the symptoms of vrudha avastha. Vrudhaavastha contributes for dhatukshaya which is the prime cause for vata prakopa and in turn responsible for the manifestation of Kampa.

Hence, these specific vitiations of vatavaha srotas impair the body’s motor functions, leading to Kampa.