Pulmonary Evaluation With Ultrasound in Different Levels of PEEP
- Conditions
- HypertensionAtelectasisLung Edema
- Interventions
- Procedure: PEEP TITRATEDDevice: Use ultrasoundDevice: Impedance tomographyOther: PEEP 4Other: Best PEEP for less collapse
- Registration Number
- NCT03211936
- Lead Sponsor
- Instituto do Cancer do Estado de São Paulo
- Brief Summary
Patients submitted to general anesthesia and artificial ventilation almost always develop pulmonary atelectasis, which can determine adverse consequences both intraoperatively and postoperatively. It is recommended to use physiological tidal volume (6 - 8 mL / kg of ideal body weight) during the intraoperative period in order to minimize the risk of lung injury. To prevent the formation of atelectasis, minimizing the risk of complications, the use of PEEP has been recommended. At present, there is no way to make an optimal adjustment of PEEP to the needs of each patient, seeking a value that keeps the alveoli open without forming atelectasis and also without areas of hyperdistension.
The aim of this study was to evaluate the agreement between the ultrasound and the electrical impedance tomography - Timpel® (TIE) to detect the beginning of the formation of areas of atelectasis after pulmonary recruitment, with decreasing PEEP values. In addition, the lung ultrasound will be validated for intraoperative use for both adequacy of PEEP, as well as quantitative analyzes of ultrasound images to assess atelectasis.
18 patients (\> 18 years) of both sexes, submitted to general anesthesia, will be prospectively studied. All patients will receive, in addition to the usual monitoring, the monitoring with the electrical impedance tomography and chest ultrasonography, after being anesthetized and under neuromuscular block, being ventilated with an inspired fraction of 50% oxygen (or greater to maintain oxygen saturation \> 96% ), Tidal volume of 6 mL / kg and respiratory rate to maintain expiratory tidal CO2 between 35-45 cmH2O.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Participants will be male and female patients, over 18 years of age, who undergo abdominal surgeries (prostatectomies and hysterectomies) and who do not have preexisting pulmonary diseases. They will be approached in the room prior to surgery, at which time the purpose of the research will be explained, besides making clear that it will not entail costs and so little any injury, scar, or damage. If accepted by the patient, the consent form will be applied.
- Exclusion criteria for the study will be: patients classified by the American Society of Anesthesiologists Physical status as ASA-3 or above, patients with obstructive and restrictive respiratory diseases, patients with predictable orotracheal intubation difficulties (eg, obese patients) who require Manipulation of the upper airways. Also excluded are patients with pacemakers and patients scheduled for procedures in the thoracic region
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description PEEP 4 PEEP 4 We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After titrated peep we setup peep 4 and maintained during the procedure. * PEEP 4 cmH2O * Use ultrasound PEEP TITRATED Use ultrasound We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After tritiated peep we setup the best peep for less collapse (using the tomography of electrical impedance) and maintained during the procedure. * PEEP titrated * Use ultrasound * Impedance tomography * Best PEEP for less collapse PEEP 4 Impedance tomography We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After titrated peep we setup peep 4 and maintained during the procedure. * PEEP 4 cmH2O * Use ultrasound PEEP 4 PEEP TITRATED We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After titrated peep we setup peep 4 and maintained during the procedure. * PEEP 4 cmH2O * Use ultrasound PEEP TITRATED PEEP TITRATED We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After tritiated peep we setup the best peep for less collapse (using the tomography of electrical impedance) and maintained during the procedure. * PEEP titrated * Use ultrasound * Impedance tomography * Best PEEP for less collapse PEEP 4 Use ultrasound We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After titrated peep we setup peep 4 and maintained during the procedure. * PEEP 4 cmH2O * Use ultrasound PEEP TITRATED Impedance tomography We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After tritiated peep we setup the best peep for less collapse (using the tomography of electrical impedance) and maintained during the procedure. * PEEP titrated * Use ultrasound * Impedance tomography * Best PEEP for less collapse PEEP TITRATED Best PEEP for less collapse We titrate peep, using tomography impedance, making ultrasound after "level by level' of peep. After tritiated peep we setup the best peep for less collapse (using the tomography of electrical impedance) and maintained during the procedure. * PEEP titrated * Use ultrasound * Impedance tomography * Best PEEP for less collapse
- Primary Outcome Measures
Name Time Method Hyperdistension during tritiate peep We acquire lung ultrasound images during tritiating peep and analyze if any patient have hyperdistension
- Secondary Outcome Measures
Name Time Method Atelectasis in the final of the procedure After the procedure we analyze with patient group have more atelectasis