Management of Peyronie's Disease With Adipose Tissue Stem Cell

Not Applicable

• Conditions: Peyronie' Disease; Erectile Dysfunction
• Interventions: Drug: Adipose tissue stem cell injection

• Registration Number: NCT02414308
• Lead Sponsor: Man Clinic for Andrology, Male Infertility and Sexual Dysfunction

Brief Summary

Erectile dysfunction is growing in prevalence all over the world and one of the most existing disease in old age patients There is many lines of treatment concerning the status of patient like psychosexual, medical, and surgical treatment But Pyronie's disease is common now among people especially diabetics, and the role of treatment still controversial in results We can start conservative treatment and then surgical treatment if fail but the outcome still not convinced Many patients refuse to fix penile prosthesis and to make operation like nesbite for probability of shortening of penis We start to use stem cell in patients have erectile dysfunction and Peyronie's disease The injection of stem cell will be at corpora cavernosa and intra dorsal penile artery under Doppler device guidance

Detailed Description

Peyronie's disease associated with erectile dysfunction nan be treated by different methods We start to treat such patients with adipose tissue stem cell Harvesting stem cell from adipose tissue and injected into corpora cavernosa and penile artery and we assess quality of erection through patient history and penile duplex and also assess plaque size and other symptoms related to Peyronie's disease

Study Timeline

• Study Start: 2013-06
• Study First Submitted: 2014-01-06
• Status Verified: 2015-04
• Study First Submitted QC: 2015-04-09
• Last Update Submitted: 2015-04-09
• Study First Posted: 2015-04-10
• Last Update Posted: 2015-04-10
• Primary Completion: 2016-05
• Study Completion: 2016-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• erectile dysfunction associated with Peyroni's diseas

Exclusion Criteria

• nil

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Adipose tissue stem cell injection	Adipose tissue stem cell injection	The stem cell will be harvested by liposuction and injection will be at corpora cavernosa and dorsal penile artery

Primary Outcome Measures

Name	Time	Method
sexual function questionnaire	2-3 months	Clinical history of patients before and after treatment Penile duplex study

Secondary Outcome Measures

Name	Time	Method
Penile plaque assessment	2-3 months	Clinical examination Patient history Penile duplex

Trial Locations

Locations (2)

Man clinic; 🇪🇬 Cairo, Egypt

Man clinic for andrology and male infertility; 🇪🇬 Cairo, Egypt