Low Dose Tadalafil 5mg for Treatment of Female Overactive Bladder Syndrome :6 Months Follow up
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Efficacy of daily low dose tadalafil 5mg in treatment of female overactive bladder syndrome: 6 months follow up
研究概览
简要总结
Evaluation of use of low dose tadalafil 5 mg daily for treatment of female OAB syndrome
详细描述
90 female patients with overactive bladder syndrome divided into 3 groups group A subjected to daily low dose tadalafil 5 mg ,group B subjected to tolterodine and group C to placebo. They are evaluated as using OAB symptoms score for 6 months follow up
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •any female with overactive bladder syndrome, urgency with or without urgency urinary incontinence
排除标准
- •Active Urinary tract infection
- •neurologic abnormality
- •Pure Stress urinary incontinence
研究组 & 干预措施
Group A Tadalafil 5 mg
30 patients subjected to Daily dose of tadalafil 5mg
干预措施: Low dose tadalafil 5 mg (Drug)
Group B Tolterodine
30 patients subjected to tolterodine 4 mg daily
干预措施: Tolterodine 4 Mg Oral Capsule, Extended Release (Drug)
Group C placebo
30 patients subjected to placebo daily
干预措施: Placebo (Drug)
结局指标
主要结局
Efficacy of daily low dose tadalafil 5mg in treatment of female overactive bladder syndrome: 6 months follow up
时间窗: 6 months
Evaluation of efficacy of tadalafil 5 mg
次要结局
未报告次要终点
研究者
Samer Morsy
Urology lecturer
Kasr El Aini Hospital