Comparison the effects of Donepezil, Galantamine,Rivastigmine and Memantine on vascular dementia.
Phase 2
Recruiting
- Conditions
- Vascular Dementia.occlusion and stenosis of cerebral and precerebral arteries (including truncus brachiocephalicus), resulting in cerebral infarction
- Registration Number
- IRCT20181210041912N1
- Lead Sponsor
- Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Patients with vascular dementia in Kerman city
Exclusion Criteria
Having any underlying condition other than diabetes, hypertension, hyperlipidemia, and ischemic heart disease, including history of depression and memory and speech impairment.
Use of any medication, such as sedative medicines and substance abuse, except medicines for controlling diabetes, hypertension, hyperlipidemia, and ischemic heart disease.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Transcranial Doppler Sonography. Timepoint: Performing transcranial doppler sonography at the beginning of the study and three months after taking any of the donepezill, memantine, galanthamine or rivastigmine drugs. Method of measurement: Doppler Sonography machine.
- Secondary Outcome Measures
Name Time Method Mini Mental State Examination. Timepoint: Measurement of the MMSE at the beginning of the study and three months after the onset of consumption, which of the drugs donepezil, memantine, galantamine or rivastigmine. Method of measurement: By number from zero to thirty.