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Goal Management Training for Patients With Schizophrenia or High Risk for Schizophrenia

Not Applicable
Completed
Conditions
Neurocognitive Disorders
Schizophrenia
Interventions
Behavioral: GMT
Registration Number
NCT03048695
Lead Sponsor
Sykehuset Innlandet HF
Brief Summary

About 85% of patients with schizophrenia have cognitive impairments, executive functions being particularly affected. Executive dysfunction, and cognitive deficits in general, are important predictors of functional outcomes, including social problem solving, activities of daily living, life satisfaction, and the ability to return to work or school.The main objective of the current study is to examine the efficacy of group-based Goal Management Training (GMT) for patients with broad schizophrenia spectrum disorders or high risk individuals with executive deficits. The short term goals are to investigate whether GMT can improve participants' ability to organize and achieve goals in everyday life in addition to improving aspects of emotional health. A long-term goal would be to establish an evidence base for nonpharmacological interventions for patients with broad schizophrenia spectrum disorders or high risk for schizophrenia. Main research questions: (1) Does a RCT with GMT delivered to patients with broad schizophrenia spectrum disorders or high risk for schizophrenia result in improved executive functioning, measured by self-reported and/or objective measures of executive functions? (2) Does GMT result in improved goal attainment in everyday life, social- and real world functioning? (3) Does GMT have a positive impact on the patients' emotional health? (4) Are there specific characteristics in patients with broad schizophrenia spectrum disorders or high risk for schizophrenia that are associated with better treatment benefit from GMT?

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
83
Inclusion Criteria
  • Being consecutively referred to treatment for a DSM-IV diagnosis of broad schizophrenia spectrum psychosis (schizophrenia, schizophreniform disorder and schizoaffective disorder) or high risk for psychosis or being treated for psychotic disorder for less than 5 years.
  • Reporting executive problems through (a) structured interview, or (b) self-report, i.e. BRIEF scale T-score < 55.
Exclusion Criteria
  • Reported ongoing alcohol or substance abuse.
  • Premorbid neurological disease or insult and/or comorbid neurological disease. ° Severe cognitive problems interfering with the capacity to participate.
  • IQ below 70.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Goal Management TrainingGMTCognitive rehabilitation
Primary Outcome Measures
NameTimeMethod
Conners Continuous Performance Test IIIBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Behavior Rating Inventory for Executive FunctionsBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Positive and Negative Syndrome ScaleBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Secondary Outcome Measures
NameTimeMethod
Dysexecutive Questionnaire (self-and informant)Baseline, immediately post-intervention and 6 months follow-up

Assessing change

Global Assessment of Functioning-Split VersionBaseline, immediately post-intervention and 6 months follow-up

Assessing change

The Hotel TaskBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Delis Kaplan Executive Function System (D-KEFS) subtestsBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Digit span and Letter-number sequencingBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Iowa Gambling TaskBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Goal Attainment ScalingBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Everyday Functioning from NORMENT Long time follow up questionnairesBaseline, immediately post-intervention and 6 months follow-up

Assessing change

General Perceived Self-Efficacy ScaleBaseline, immediately post-intervention and 6 months follow-up

Assessing change

The Perceived Quality of Life ScaleBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Rosenberg self-esteem scaleBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Cognitive Failures QuestionnaireBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Social Functioning ScaleBaseline, immediately post-intervention and 6 months follow-up

Assessing change

Hopkins Symptom Checklist 10Baseline, immediately post-intervention and 6 months follow-up

Assessing change

Trial Locations

Locations (1)

Sykehuset Innlandet Reinsvoll

🇳🇴

Reinsvoll, Norway

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