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Evaluation of Executive Function With Virtual Reality Among People With Schizophrenia

Not Applicable
Conditions
Schizophrenia
Interventions
Device: Virtual Reality - Virtual Interactive Supermarket
Registration Number
NCT03146364
Lead Sponsor
HaEmek Medical Center, Israel
Brief Summary

This Cross-sectional Study Included Patients that diagnosed with schizophrenia, aged 18-55, 20 of which hospitalized in mental health department and 20 in medical follow-up.

Different test will be administered, in two or three sessions, to evaluate cognitive ability, function ability and participation.

The results of the VIS shopping task performance (statically \& dynamically) and its correlation with the cognitive and function tests as well as the participation questionnaire will be examined. These findings will indicate whether the shopping task is valid to assess executive functions for people with schizophrenia and whether it is ecologically valid.

Detailed Description

Background:

Schizophrenia often reflect by decrease in executive functions that may cause difficulty in Instrumental Activities of Daily Living (IADL). We've found it very difficult to simulate these functions with the existing tools in the clinic and to assess IADL accordingly.

The use of Virtual Reality (VR) became popular in the last decade to overcome these limitations in clinical practice and assessment of functioning in IADL. VR is a computer program that simulates a functional environment in which the subject impacts on events through various actions. Recent studies indicated that VR can be used to assess cognitive abilities and functioning of population with schizophrenia. As far as we know, no researches were performed using Virtual Interactive Shopping (VIS) in this population, nor did dynamic evaluation was used to identify potential learning abilities. The aim of this study is to examine the validity of the shopping task in the VIS, performed statically and dynamically, in order to assess executive function, and the ability to reflect cognitive, functional and participation ability among people that diagnosed with schizophrenia.

Method:

This Cross-sectional Study Included Patients that diagnosed with schizophrenia, aged 18-55, 20 of which hospitalized in mental health department and 20 in medical follow-up.

Different test will be administered, in two or three sessions, to evaluate cognitive ability, function ability and participation.

The results of the VIS shopping task performance (statically \& dynamically) and its correlation with the cognitive and function tests as well as the participation questionnaire will be examined. These findings will indicate whether the shopping task is valid to assess executive functions for people with schizophrenia and whether it is ecologically valid.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Schizophrenia or Scizoeffective diagnosis, Hebrew language proficiency, three weeks of anti-psychotic drug treatment
Exclusion Criteria
  • score of under 70 in the 3MS (screen test), physical disability, neurological diagnosis (ex. dementia)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Hospitalization patientsVirtual Reality - Virtual Interactive Supermarketpatients in psychiatric hospitalization will take part in tests at Virtual Reality - Virtual Interactive Supermarket environment (diagnosis)
Ambulatory patientsVirtual Reality - Virtual Interactive Supermarketpatients being treated in a clinic will take part in tests at Virtual Reality - Virtual Interactive Supermarket environment (diagnosis)
Primary Outcome Measures
NameTimeMethod
Modified 4 item testthrough study completion, an average of 1 year

"buy" 4 items with budget constraints, using the VIS

Secondary Outcome Measures
NameTimeMethod
Revised Observed Tasks of Daily Living (OTDL-R)through study completion, an average of 1 year

evaluation of IADL using various tasks include problem solving

Trail Making Test A & B (TMT)through study completion, an average of 1 year

The Trail Making Test is an accessible neuropsychological instrument that provides the examiner with information on a wide range of cognitive skills and can be completed in 5-10 min.

Executive Function Performance Test (EFPT)through study completion, an average of 1 year

executive function assessment using 5 different tasks

The positive and negative syndrome scale (PANSS)through study completion, an average of 1 year

The Positive and Negative Syndrome Scale (PANSS) was developed out of the need for a well-operationalized method of assessing these syndromes in schizophrenia, including their relationship to one another and to global psychopathology

Adults Subjective Assessment of Participationthrough study completion, an average of 1 year

participation questionnaire that examine the level of engagement in different occupations

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