Exploring Hand Function in People With Schizophrenia Based on Perspective of Sensorimotor Control

Completed

• Conditions: Schizophrenia
• Interventions: Other: no intervention

• Registration Number: NCT04941677
• Lead Sponsor: National Cheng-Kung University Hospital

Brief Summary

The study aims to explore the hand function in people with schizophrenia in the chronic stage.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-17
• Study First Submitted: 2021-06-20
• Study First Submitted QC: 2021-06-21
• Study First Posted: 2021-06-28
• Primary Completion: 2022-07-31
• Study Completion: 2022-12-31
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-01
• Last Update Posted: 2024-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Age between 20-65 years old
• Diagnosis with schizophrenia or schizoaffective disorder by psychiatrists according to DSM5.
• Remaining the same antipsychotics and the symptom was stable for at least one month before the study.
• Be able to follow comments and have sufficient cognitive ability assessed by Mini-Mental State Examination score >24

Exclusion Criteria

• Substance abuse or other medical conditions that may affect movements.
• Using other non-antipsychotics that will affect movements in the same period.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
schizophrenia group	no intervention	No intervention age between 20-65, diagnosed schizophrenia by DSM-5.

Primary Outcome Measures

Name	Time	Method
Semmes Weinstein Monofilaments	baseline	Semmes Weinstein Monofilaments is used to assess cutaneous pressure thresholds.
Pinch-holding-up-activity test	baseline	The pinch apparatus is aims to assess the ability to modulate pinch force to movement-induced load fluctuations in a pinch-holding-up activity (PHUA).
Manual Tactile Test	baseline	Manual tactile test (MTT) aims to assess the capacity of barognosis, roughness differentiation and stereognosis.
Purdue pegboard test	baseline	The purpose for Purdue pegboard test is to measure manipulative dexterity including unimanual and bimanual hand dexterity.
The Valpar 8 simulates assembly work assessment	baseline	Valpar8 simulates the light work and assess the ability of manual dexterity and motor coordination.

Secondary Outcome Measures

Name	Time	Method
Self-reported version of the graphic Personal and Social Performance (SRG-PSP)	baseline	The self-reported version of the graphic personal and social performance is a self-report scale that aims to assess functional performance.

Trial Locations

Locations (1)

National Cheng-Kung University; 🇨🇳 Tainan, Taiwan