Comparison of Brain Volumes of Preterm Infants Measured by Two Dimensional Ultrasonography and Cranial Magnetic Resonance Imaging
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Central Nervous System Vulnerabilities in Preterm Infants
- Sponsor
- Ankara City Hospital Bilkent
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Results of two different brain volumes
- Last Updated
- 5 years ago
Overview
Brief Summary
Cranial USG is simple and easy method to assess preterm infant brain. Some studies showed that brain volumes of preterm infants could be calculated by measurement of 2D distances. Our aim in this study was to compare brain volume obtained by USG and MRI.
Detailed Description
All preterm infants less than 32 weeks of gestational age undergo cranial USG examination routinely at least, in the first week of life, at the end of first month and corrected age 36 weeks and 40 weeks. We will performa all USG mesurements with measureing intracranial hegiht, anteroposterior diameter, biparietal diamater, ventriccular height, thalamo-occipital distance and ventricular index. We will calculate the brain volume as a spheric geometric shape than we will calculate two ventricles as conical shapes. Absolute brain volume will be calculating by substracting two ventricles from total brain volume. At 40 weeks of age we will perform a cranial MRI to show exact brain volume and we will ccompare two different methods.
Investigators
Fuat Emre Canpolat
Assoc Prof Fuat Emre CANPOLAT MD
Ankara City Hospital Bilkent
Eligibility Criteria
Inclusion Criteria
- •All preterm infants under 32 weeks of gestational age and birth weight between 800-1200 grams
- •Born in our hospital
- •Alive during discharge
Exclusion Criteria
- •congenital anomalies
- •cranial bleeding
- •early death
Outcomes
Primary Outcomes
Results of two different brain volumes
Time Frame: 6 months
Patients in cohort will have both USG and cranial MRI