跳至主要内容
临床试验/NCT02848755
NCT02848755已完成不适用

Neonatal Cranial Ultrasonography for Measuring Brain Volumes of Very Low Birth Weight Infants

Zekai Tahir Burak Women's Health Research and Education Hospital1 个研究点 分布在 1 个国家目标入组 341 人开始时间: 2017年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
341
试验地点
1
主要终点
measurements of ventricular indexes of preterm infants

研究概览

简要总结

Neonatal cranial ultrasound (US) remains the method of choice to detect brain injury in high risk preterm infants on neonatal intensive care units (NICU). It is a non-invasive, inexpensive bedside tool and examinations can be repeated as often as necessary without major disturbance of vulnerable infants. The anterior and posterior fontanelles from excellent acoustic windows to examine the deep midline and periventricular regions of the brain.Some data demonstrated that cerebral palsy can be accurately predicted with US. However, cranial US is not very suitable for investigating cortical regions or structures in the posterior fossa. There is limited data for very preterm infants.The investigators aimed to measure ventricular index, cranial height, biparietal diameter and calculate brain volume in a huge number of infants.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Day 至 40 Weeks(Child)
性别
All
接受健康志愿者

入选标准

  • both gender
  • <1500 gr <32 week-
  • 1-28 days neonates

排除标准

  • Anomalies and no viability

结局指标

主要结局

measurements of ventricular indexes of preterm infants

时间窗: 12 months

measuring distance with 2D USG

measurements of brain volumes of preterm infants

时间窗: 12 months

subtracting the ventricular volumes from the total brain volume measured with 2D

次要结局

未报告次要终点

研究者

发起方
Zekai Tahir Burak Women's Health Research and Education Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Gulsum Kadioğlu Simsek

Uzm Dr

Zekai Tahir Burak Women's Health Research and Education Hospital

研究点 (1)

Loading locations...

相似试验