Neonatal Cranial Ultrasonography for Measuring Brain Volumes of Very Low Birth Weight Infants
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 341
- 试验地点
- 1
- 主要终点
- measurements of ventricular indexes of preterm infants
研究概览
简要总结
Neonatal cranial ultrasound (US) remains the method of choice to detect brain injury in high risk preterm infants on neonatal intensive care units (NICU). It is a non-invasive, inexpensive bedside tool and examinations can be repeated as often as necessary without major disturbance of vulnerable infants. The anterior and posterior fontanelles from excellent acoustic windows to examine the deep midline and periventricular regions of the brain.Some data demonstrated that cerebral palsy can be accurately predicted with US. However, cranial US is not very suitable for investigating cortical regions or structures in the posterior fossa. There is limited data for very preterm infants.The investigators aimed to measure ventricular index, cranial height, biparietal diameter and calculate brain volume in a huge number of infants.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 40 Weeks(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •both gender
- •<1500 gr <32 week-
- •1-28 days neonates
排除标准
- •Anomalies and no viability
结局指标
主要结局
measurements of ventricular indexes of preterm infants
时间窗: 12 months
measuring distance with 2D USG
measurements of brain volumes of preterm infants
时间窗: 12 months
subtracting the ventricular volumes from the total brain volume measured with 2D
次要结局
未报告次要终点
研究者
Gulsum Kadioğlu Simsek
Uzm Dr
Zekai Tahir Burak Women's Health Research and Education Hospital
