Comparison of the oocyte quality in patients with poor ovarian response undergone two triggering methods.

Phase 3

• Conditions: Infertility.; Complication associated with artificial fertilization, unspecified; N98.9

• Registration Number: IRCT20190409043207N2
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 122

Inclusion Criteria

Age more than 40 years or other risk factors for poor ovarian response.
Less than three oocytes in the previous IVF cycle
Abnormal ovarian reserve test
Two histories of poor ovarian response following receiving maximal stimulation

Exclusion Criteria

Severe male factor
Untreated endocrine disorders
Severe uterine anomaly

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate. Timepoint: Four weeks after positive beta hCG. Method of measurement: Fetal heart activity by trans-vaginal ultrasonography.

Secondary Outcome Measures

Name	Time	Method
Biochemical pregnancy rate. Timepoint: 14 days after embryo transfer. Method of measurement: Positive B-HCG.;Implantation rate. Timepoint: 4 weeks after embryo transfer. Method of measurement: It is defined as the numbers of gestational sacs that detected throughout sonography per number of embryos transferred (100 embryo).;Abortion rate. Timepoint: Before 20th weeks of gestation. Method of measurement: Observation and counting.;COC counting. Timepoint: The day of oocyte puncture. Method of measurement: Counting.;MII oocyte number. Timepoint: The day of puncture. Method of measurement: Counting.;2PN number. Timepoint: 1 day after fertilization. Method of measurement: Counting.;Estradiol level. Timepoint: In the day of hCG injection. Method of measurement: Biochemical measurements in the blood.;Embryo grading. Timepoint: 3 days after puncture. Method of measurement: Observation and grading according to the embryo references.