Quality of life, gross motor function, and actual everyday physical activity level in children with spastic Cerebral Palsy: (cost)effectiveness of combined treatment with multilevel botulinum-toxin injections and intensive functional physiotherapy.

ZonMW0 个研究点开始时间: 2009年5月4日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•Children with spastic Cerebral Palsy aged 4-12 years whose lower extremity is involved and who have been selected for treatment with multilevel botulinum toxin injections followed by intensive physiotherapy are eligible candidates.
•Spastic CP will be diagnosed according to the guidelines of the Dutch Institute for Healthcare Improvement. Only children classified as levels I-III with the Gross Motor Function Classification System (GMFCS) will be included for the study because they are (household) ambulators.
•Are the trial subjects under 18? yes
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) no
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•The children’s´ motor selectivity should be sufficient (to be measured by valid selectivity test), and they are excluded in case of surgery <12 months before the study and in case of BtA treatment <6 months preceding the study. Children will also be excluded when severe contractures are present, when they are cognitively unable to understand instructions, or when there is co-morbidity (e.g. visual disability, severe epilepsis) that affects their everyday functioning.

发起方