The influence of high-intensity compared with moderate-intensity exercise training on the health of colorectal cancer survivors: a randomised controlled trial

Completed

• Conditions: Colorectal cancer; Cancer survivorship; Cancer - Bowel - Back passage (rectum) or large bowel (colon); Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12615000908538
• Lead Sponsor: The University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-09-01
• Study Completion: 2016-11-30
• Last Update Posted: 28 June 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 57

Inclusion Criteria

i.Aged over 18 years old.
ii.Greater than or equal to one-month post-treatment for colorectal cancer.

Exclusion Criteria

i.Medicated with insulin or any insulin sensitising agents (biguanides, thiazolidinediones, sulfonylureas or meglitinides).
ii.Any musculoskeletal, neurological, respiratory, metabolic or cardiovascular conditions that may prevent safe completion of the exercise demands of the study as determined by the research team and the participant's primary healthcare physician.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Insulin-like growth factor (IGF)-1, analysed using a commercially available plasma enzyme linked immunosorbent assay (ELISA) [Baseline (0 weeks); Midpoint (4 weeks); Endpoint (8 weeks); Follow-up (12 weeks)];IGF binding protein (IGFBP) - 3, analysed using a commercially available plasma ELISA[Baseline (0 weeks); Midpoint (4 weeks); Endpoint (8 weeks); Follow-up (12 weeks)<br>];IGF-2, analysed using a commercially available plasma ELISA[Baseline (0 weeks); Midpoint (4 weeks); Endpoint (8 weeks); Follow-up (12 weeks)]